The Maudlin challenge (see this blog post for details) was a worthy criticism that spurred further development of TI. However, it is not at all the fatal objection that it was taken to be for over a decade.
The final version of the refutation of the Maudlin challenge including Marchildon’s approach, published in SHPMP, can be seen here:
Also, there is increasing recognition by quantum foundations researchers that spacetime may not be the whole story, and that spacetime events may arise from sub-empirical quantum processes. This concept will be explored for the layperson and interested researcher in my upcoming book, Understanding Our Unseen Reality: Resolving Quantum Riddles (published by Imperial College Press). Stay tuned!